Anti-Aging & Longevity Rx Treatments for the Elites at the Jersey Shore
Where Modern Science & Luxury Wellness Come Together
At Mirelle Institute for Anti-Aging Medicine, we unite cutting-edge longevity science with refined aesthetic medicine to help you look, feel, and function at your absolute best. Our approach is designed for discerning men and women who expect more than standard treatments—those who value personalized care, cellular-level results, curated prescription-grade skincare, and a luxury experience that aligns seamlessly with their lifestyle.
Every program at Mirelle is rooted in precision medicine and guided by a deep understanding of the biology of aging. From bioidentical hormone optimization and advanced peptide therapy to regenerative treatments, NAD⁺ infusions, exosomes, pharmaceutical-grade skincare, and sophisticated aesthetic rejuvenation, each protocol is meticulously tailored to support cellular repair, restore balance, and reverse key drivers of biological aging. The result is not simply looking younger—but living with greater vitality, clarity, confidence, and longevity.
This is precision longevity care — elegant, intelligent, and deeply effective.
THE MIRELLE ANTI-AGING APPROACH
Our Clinical Philosophy
Peptides do not override physiology — they amplify it.
At Mirelle, we ensure the body is ready before we ask it to respond.
A Personalized Blueprint for Lifelong Vitality
Discover whether advanced peptide therapy is appropriate for you.
Begin with acomprehensive metabolic and longevity evaluation at Mirelle Institute for Anti-Aging Medicine.
Peptide Supplements for Longevity & Cellular Support
In Partnership with Healthgevity
At Mirelle Institute for Anti-Aging Medicine, we believe longevity care begins with education, transparency, and evidence-informed options. As part of our commitment to patient empowerment, we have partnered with Healthgevity, a company that offers peptides formulated as dietary supplements designed to support cellular health, recovery, and healthy aging pathways.
These products are non-injectable, over-the-counter supplements and are not prescription medications. They may be appropriate for individuals seeking foundational support or those exploring peptide-related pathways before considering clinician-guided therapies.
Frequently Asked Questions
What are peptides, and why are they used in longevity medicine?
Peptides are short chains of amino acids that act as biological messengers, signaling specific repair, metabolic, immune, and regenerative pathways in the body. In clinical medicine, peptides are used to support:
Cellular repair and tissue regeneration
Metabolic efficiency and body composition
Immune modulation
Skin, hair, and connective tissue integrity
Cognitive and sexual wellness
At Mirelle, peptides are prescribed only after comprehensive metabolic testing, because signaling without physiologic readiness can lead to poor outcomes.
What makes Mirelle’s peptide program different?
Mirelle does not prescribe peptides based on trends or symptoms alone.
Before any peptide is considered, we perform stringent metabolic and inflammatory testing, which may include:
Comprehensive metabolic and cardiovascular labs
Hormonal and thyroid evaluation
Inflammatory and cytokine profiling
ECM and tissue-quality assessment (when indicated)
Peptides are prescribed only when the body’s internal environment is appropriate to receive and respond to them.
What is needle-free (buccal/oromucosal) peptide delivery?
Needle-free peptide delivery uses the oral mucosa (buccal or sublingual tissue) to allow certain compounds to be absorbed directly into circulation, bypassing some first-pass metabolism.
This technology is an active area of pharmaceutical research, particularly for patients seeking alternatives to injections. Not all peptides are suitable for this route, which is why clinical selection and formulation matter.
At Mirelle, needle-free peptide therapy is available only through clinician oversight, not retail sale.
Which peptides are available in needle-free form at Mirelle?
Based on current scientific understanding and formulation feasibility, Mirelle offers select non-injectable peptide options, including:
CJC-1295
What it supports:
Metabolic signaling, growth hormone optimization, body composition
Clinical context:
CJC-1295 is a growth hormone–releasing hormone (GHRH) analog studied in humans for its ability to stimulate endogenous GH and IGF-1 production.
Why medical oversight matters:
Growth signaling must be carefully matched to metabolic, inflammatory, and cardiovascular status.
GHK-Cu (Copper Peptide)
What it supports:
Skin integrity, collagen signaling, tissue repair, hair health
Clinical context:
GHK-Cu is a naturally occurring peptide studied for its role in extracellular matrix remodeling and regenerative signaling.
BPC-157
What it supports:
Tissue repair signaling, gut and connective tissue support
Clinical context:
BPC-157 has extensive preclinical research and limited human trial experience, primarily in inflammatory and tissue-repair contexts.
Thymosin Alpha-1
What it supports:
Immune modulation and resilience
Clinical context:
Thymosin Alpha-1 has been studied in multiple human clinical trials for immune regulation and inflammatory balance.
PT-141 Plus
What it supports:
Sexual wellness and desire signaling
Clinical context:
PT-141 (bremelanotide) is FDA-approved in injectable form for specific indications. Non-injectable formulations are considered off-label and require careful patient selection and education.
Glutathione
What it supports:
Cellular antioxidant capacity, detoxification pathways
Clinical context:
Sublingual and buccal delivery systems for glutathione have been studied as a method to enhance convenience while supporting systemic levels.
NAD⁺
What it supports:
Cellular energy metabolism, mitochondrial function
Clinical context:
NAD⁺ biology is well established, though delivery route and formulation are critical for effectiveness.
Why are GLP-1 and GIP therapies not included in the needle-free category?
At Mirelle, GLP-1 and GIP therapies are administered exclusively in injectable form.
This is intentional.
Injectable delivery remains the most clinically validated, predictable, and evidence-supported route for incretin-based therapies. We do not compromise outcomes by using inferior delivery methods for medications that require precise pharmacokinetics.
Is needle-free peptide therapy right for everyone?
No — and that is by design.
Peptide therapy is not prescribed if:
Metabolic or inflammatory markers are uncontrolled
Cardiovascular risk is high without optimization
Hormonal or thyroid instability is present
The body is not prepared to respond appropriately
This protects patients and ensures results.
Why is this technology only available at Mirelle?
Because this approach requires:
Advanced diagnostic testing
Medical decision-making
Controlled sourcing
Ongoing monitoring
Ethical prescribing standards
Mirelle does not sell peptides as retail products.
We deliver medicine, not shortcuts.
Your anti-aging and longevity plan is built around three pillars:
✔ Cellular Optimization
Mitochondrial support, NAD+ therapy, peptides, detox pathways, oxidative stress reduction.
✔ Hormonal Balance & Metabolic Repair
BHRT, TRT, thyroid support, metabolic hormones, insulin control, adrenal optimization.
✔ Aesthetic Regeneration
Advanced skin tightening, facial balancing, biostimulators, regenerative lifts, and targeted anti-aging skincare.
Each patient receives a fully personalized roadmap based on diagnostics, symptoms, goals, and lifestyle.
Advanced Longevity Treatments Offered at Mirelle
Advanced Precision Medicine — Without Painful Injections. Discover Needle-Free Peptide Therapy at Mirelle
At Mirelle Institute for Anti-Aging Medicine, we are proud to introduce a new generation of needle-free peptide technology, available exclusively through our clinic.
This advanced delivery platform allows select peptides to be administered without injections, while still respecting the science, safety, and medical rigor required for peptide therapy.
This is not “over-the-counter” peptide use.
This is precision longevity medicine.
Peptide Therapy- Injectable and Non-Injectable Peptides
Targeted peptides support fat loss, muscle development, immune strength, better sleep, collagen production,
and hormonal balance.
Which peptides are available in needle-free form at Mirelle?
Based on current scientific understanding and formulation feasibility, Mirelle offers select non-injectable peptide options, including:
CJC-1295
What it supports:
Metabolic signaling, growth hormone optimization, body composition
Clinical context:
CJC-1295 is a growth hormone–releasing hormone (GHRH) analog studied in humans for its ability to stimulate endogenous GH and IGF-1 production.
Why medical oversight matters:
Growth signaling must be carefully matched to metabolic, inflammatory, and cardiovascular status.
GHK-Cu (Copper Peptide)
What it supports:
Skin integrity, collagen signaling, tissue repair, hair health
Clinical context:
GHK-Cu is a naturally occurring peptide studied for its role in extracellular matrix remodeling and regenerative signaling.
BPC-157
What it supports:
Tissue repair signaling, gut and connective tissue support
Clinical context:
BPC-157 has extensive preclinical research and limited human trial experience, primarily in inflammatory and tissue-repair contexts.
Thymosin Alpha-1
What it supports:
Immune modulation and resilience
Clinical context:
Thymosin Alpha-1 has been studied in multiple human clinical trials for immune regulation and inflammatory balance.
PT-141 Plus
What it supports:
Sexual wellness and desire signaling
Clinical context:
PT-141 (bremelanotide) is FDA-approved in injectable form for specific indications. Non-injectable formulations are considered off-label and require careful patient selection and education.
Glutathione
What it supports:
Cellular antioxidant capacity, detoxification pathways
Clinical context:
Sublingual and buccal delivery systems for glutathione have been studied as a method to enhance convenience while supporting systemic levels.
NAD⁺
What it supports:
Cellular energy metabolism, mitochondrial function
Clinical context:
NAD⁺ biology is well established, though delivery route and formulation are critical for effectiveness.
What makes Mirelle’s peptide program different?
At Mirelle, peptides are not “trendy add-ons.” They are precision tools—used only after stringent metabolic testing and medical clearance, because peptide signaling is only as effective (and safe) as the physiology receiving it.
What is “buccal / oromucosal” delivery?
Buccal/sublingual delivery uses the oral mucosa to bypass part of first-pass metabolism and improve convenience. It’s a promising platform, but it’s also scientifically demanding—especially for larger, fragile molecules like peptides, which is why advanced strategies (films, mucoadhesive systems, permeation approaches) are an active research focus.
Are all peptides equally effective as buccal delivery?
No. In general, macromolecules are harder to deliver across oral mucosa, and successful translation depends on molecular size, stability, formulation, and permeability. Buccal delivery of biologics has reached clinical-trial exploration (e.g., insulin strategies), but variability and efficacy challenges remain.
How does buccal delivery compare to injections?
Direct bloodstream entry:
Injection: Yes
Buccal: Yes (indirect, enhanced by formulation)
First-pass metabolism:
Injection: No
Buccal: Minimal
Pain:
Injection: Yes
Buccal: No
Patient convenience:
Injection: Moderate
Buccal: High
Need for formulation:
Injection: Lower
Buccal: Higher
Buccal delivery is a patient-centered, needle-free option when supported by formulation science and clinical oversight.
NAD+ - Oral, IV Therapy & Injections
What is NAD+?
NAD+ is a foundational coenzyme involved in cellular energy metabolism and redox biology.
This powerful coenzyme fuels every cell in the body. Our NAD+ protocols improve cognitive sharpness, energy, metabolism, sleep, and cellular repair — a foundational treatment for slowing aging.
Is buccal NAD+ clinically proven?
Evidence is far stronger for NAD+ biology than for buccal NAD+ pharmacokinetics specifically. For oromucosal delivery platforms, the broader science focuses on what it takes to move molecules across mucosa reliably.
What does NAD+ support?
Cellular energy metabolism, mitochondrial function
Clinical context:
NAD⁺ biology is well established, though delivery route and formulation are critical for effectiveness.
CJC-1295 (GHRH Analog)
What is CJC-1295?
CJC-1295 is a long-acting analog of growth hormone–releasing hormone (GHRH) designed to stimulate the body’s own pulsatile growth hormone signaling.
What does the clinical science show?
In controlled human studies, CJC-1295 produced sustained, dose-dependent increases in GH and IGF-1 with a multi-day duration of effect.
Is buccal CJC-1295 supported by strong clinical evidence?
Buccal delivery of biologics is an evolving field, but peptide performance can be variable and formulation-dependent.
Who may be a candidate at Mirelle?
Patients seeking metabolic optimization may be considered only after lab-based clearance and individualized risk review.
GHK-Cu (Copper Peptide)
What is GHK-Cu?
GHK-Cu is a naturally occurring copper-binding peptide studied for tissue remodeling and skin-supportive signaling.
What does the literature suggest?
Preclinical work supports roles in healing models (including angiogenesis and tissue repair signaling) using advanced formulations.
Is buccal delivery proven for GHK-Cu?
Oromucosal systems are promising in general, but peptide absorption depends on formulation and molecular constraints
BPC-157
What is BPC-157?
BPC-157 is a synthetic pentadecapeptide that has been explored largely in GI and tissue-healing research.
What is the level of evidence?
The published literature includes reviews and reports noting investigation and prior trial experience in inflammatory bowel disease contexts, with extensive preclinical data.
Is buccal BPC-157 established?
Buccal delivery for peptides is highly formulation-dependent
Thymosin Alpha-1 (Thymalfasin)
What is Thymosin Alpha-1?
Thymosin Alpha-1 is an immune-modulating peptide studied in a variety of clinical contexts.
What does the research show?
Systematic and narrative reviews summarize human clinical trial experience and immunologic rationale.
Buccal delivery?
Buccal (oromucosal) delivery of peptides is an emerging science with published research on mucosal absorption strategies.
Thymosin Alpha-1 shares characteristics with other bioactive peptides that may be amenable to transmucosal delivery when formulated appropriately.
At Mirelle, we work with advanced compounding partners and leverage the best available science and technology to optimize peptide delivery — including oromucosal platforms — when clinically appropriate.
Can Thymosin Alpha-1 be delivered without injections?
Emerging research supports the feasibility of peptide delivery across the oral mucosa under specialized formulation conditions. While injectable Thymosin Alpha-1 remains the standard in clinical research, Mirelle integrates advanced transmucosal science — backed by peer-reviewed drug delivery research — for select peptide protocols when medically appropriate
Thymosin Alpha-1 is typically administered parenterally (injection) in standardized clinical studies. However, the science of buccal (sublingual/oromucosal) delivery of peptides is advancing, with multiple published studies demonstrating that peptides and small proteins can be absorbed across the oral mucosa when paired with appropriate delivery systems.
A foundational review on this topic can be found here: Advances in oral mucosal peptide and protein delivery — PubMed:
At Mirelle, we leverage state-of-the-art buccal peptide delivery technologies — informed by emerging research — to offer needle-free options when safety and formulation science support therapeutic rationale.
PT-141 Plus (Bremelanotide)
What is PT-141?
PT-141 (bremelanotide) is a melanocortin receptor agonist that acts centrally on the brain — not peripherally on hormones — to support sexual desire and arousal in women and men.
It is FDA-approved in injectable form (Vyleesi®) for:
Premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD)
Key distinction: PT-141 works on neuroendocrine signaling, not testosterone or estrogen pathways.
Important Medical Disclosure:
PT-141 Plus™ delivered via buccal administration is an off-label use. Injectable bremelanotide is the FDA-approved route. Mirelle Institute for Anti-Aging Medicine prescribes PT-141 only after comprehensive medical evaluation and informed consent.
Is PT-141 supported by clinical evidence?
Yes — PT-141 is supported by multiple randomized, placebo-controlled clinical trials, which demonstrated statistically significant improvements in desire, arousal, and sexual distress.
Clayton et al., Journal of Sexual Medicine (Phase 3 trials)
These trials confirm mechanism, efficacy, and safety parameters.
What does the clinical evidence of PT-141 suggest?
Human studies in men (early phase/clinical trials) showed PT-141 could improve erectile response, including in some men who did not respond adequately to sildenafil.
Common side effects reported include nausea, flushing, headache, and transient increases in blood pressure—which is why cardiovascular screening matters.
What PT-141 does in men?
PT-141 ( bremelanotide ) can be used in men for erectile dysfunction in certain situations, but the key is to position it correctly.
PT-141 is a central (brain-mediated) melanocortin receptor agonist. Unlike PDE5 inhibitors (Viagra/Cialis), it doesn’t primarily work by increasing penile blood flow directly. It can enhance sexual desire/arousal signaling and may improve erectile response, especially when the issue is neurogenic/psychogenic, low desire, or poor arousal signaling.
Who is PT-141 for?
Female population:
Premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD)
Male population:
Men with ED + low desire/arousal
Men with performance anxiety/psychogenic overlay
Men who are partial/non-responders to PDE5 inhibitors
Men on SSRIs/SNRIs with sexual dysfunction (after medication review)
What are the contraindications of PT-141 ?
Not ideal / caution
- Uncontrolled hypertension
- Recent cardiovascular events
- Significant nausea sensitivity
- Patients needing a predictable “on-demand” effect comparable to PDE5s
What makes PT-141 Plus™ at Mirelle different?
At Mirelle, PT-141 Plus™ is offered via advanced needle-free buccal (oromucosal) delivery, eliminating the need for injections while prioritizing patient comfort and adherence.
Buccal delivery allows absorption through the highly vascular oral mucosa, bypassing first-pass liver metabolism and supporting systemic exposure when appropriately formulated.
Can PT-141 Plus™ be combined with other therapies?
Yes — when clinically appropriate.
PT-141 Plus™ may be integrated into a broader Mirelle Intimate Health Program that can include:
Testosterone optimization (when indicated)
Metabolic and cardiovascular optimization
Lifestyle and stress-reduction strategies
Pelvic floor and regenerative therapies
Everything is coordinated — nothing is prescribed in isolation.
Why choose Mirelle for PT-141 Plus™?
Because Mirelle does not treat erectile dysfunction as a single-symptom problem.
We address:
- Neuroendocrine signaling
- Metabolic health
- Cardiovascular risk
- Psychological and lifestyle contributors
We offer PT-141 therapy in conjunction with regenerative treatments such as the P-Shot® and O-Shot® to ensure proper cell communication and functionality.
All within a luxury, medically rigorous environment.
Gluthatione- Cellular Defense. Detoxification. Longevity.
How is glutathione administered at Mirelle?
At Mirelle Institute for Anti-Aging Medicine, glutathione is not offered as a generic “antioxidant boost.” It is prescribed as part of a precision longevity and metabolic optimization strategy, guided by testing and clinical oversight.
Mirelle offers two medically guided delivery options, selected based on patient needs, goals, and physiology:
Intravenous (IV) Glutathione
Needle-Free Buccal (Oromucosal) Glutathione
Both require clinical evaluation prior to initiation.
What is glutathione?
Glutathione is the body’s master intracellular antioxidant, present in nearly every cell. It plays a critical role in:
Cellular detoxification
Neutralizing oxidative stress
Supporting mitochondrial function
Immune regulation
Liver health and toxin clearance
Low glutathione levels are associated with accelerated aging, inflammation, chronic illness, and impaired detoxification.
Why do glutathione levels decline with age?
Glutathione production decreases due to:
Aging
Chronic stress and inflammation
Environmental toxin exposure
Alcohol consumption
Certain medications
Illness and metabolic dysfunction
This decline increases oxidative damage at the cellular level.
Who is IV glutathione best suited for?
IV glutathione may be recommended for patients seeking:
Intensive detoxification support
High oxidative stress reduction
Immune or inflammatory support
Adjunct therapy during metabolic or longevity programs
Enhanced recovery or cellular repair
IV therapy is often chosen when maximum bioavailability is clinically desired.
Needle-Free Buccal Glutathione - What is buccal glutathione?
Buccal (or oromucosal) glutathione is administered through the oral mucosa, allowing absorption through the richly vascularized tissues of the mouth.
This route:
Avoids GI degradation seen with swallowed supplements
Minimizes first-pass liver metabolism
Offers a needle-free, patient-friendly option
Is buccal glutathione supported by science?
Yes. Pharmaceutical research supports the feasibility of sublingual and buccal glutathione delivery using specialized formulations.
Peer-reviewed studies demonstrate:
Development of mucoadhesive sublingual films for glutathione
Measurable permeation across oral mucosal tissue
Improved convenience compared to oral capsules
Reference: Development and evaluation of sublingual glutathione films
https://pubmed.ncbi.nlm.nih.gov/29656064/
Additionally, broader drug-delivery literature confirms that peptides and biologically active molecules can be absorbed via the oral mucosa when properly formulated.
Reference: Advances in oral mucosal peptide and protein delivery
Is oral glutathione the same as buccal glutathione?
No.
Swallowed oral glutathione capsules are largely degraded in the digestive tract. Buccal glutathione is designed to be absorbed through the oral lining, not the stomach or intestines.
Can glutathione be combined with other longevity therapies?
Yes. Glutathione is often integrated with:
Metabolic optimization programs
Peptide therapy
NAD⁺ support
Hormone optimization
IV nutrient therapies
Everything is coordinated within a comprehensive plan.
Hormone Replacement Therapy (BHRT & TRT)
Precision Hormone Medicine for Women and Men
At Mirelle Institute for Anti-Aging Medicine, hormone therapy is not about replacing a number on a lab report — it is about restoring neuroendocrine balance, metabolic resilience, and long-term vitality using science-guided, individualized care.
Balanced hormones are essential for youthfulness, energy, libido, healthy weight, mental clarity, and long-term vitality.
Bio-Identical Hormones for Women
Precision Hormone Optimization for Women
What is Bio-Identical Hormone Replacement Therapy (BHRT)?
Bio-identical hormone replacement therapy uses hormones that are molecularly identical to those produced by the human body. These hormones interact with receptors in the brain and tissues in a way that mirrors natural physiology.
BHRT may include estrogen (estradiol, estriol), progesterone, testosterone, DHEA, pregnenolone, or thyroid hormones — prescribed only when clinically indicated.
How is BHRT different from conventional hormone therapy?
Conventional hormone therapy often relies on synthetic or non-human hormones, standardized dosing, and symptom-based prescribing.
At Mirelle, BHRT is:
Individualized — based on labs, symptoms, and physiology
Bio-identical — structurally identical to human hormones
Precision-guided — adjusted over time, not “set and forget”
Root-cause focused — addressing neuroendocrine signaling, not just hot flashes
Who is a candidate for BHRT?
BHRT may be appropriate for women and men experiencing symptoms related to hormonal decline or imbalance, including:
Perimenopause or menopause symptoms
Andropause / testosterone deficiency
Fatigue, brain fog, mood changes
Sleep disruption
Weight gain or metabolic slowdown
Low libido or sexual dysfunction
Loss of muscle tone or bone density
However, not everyone is a candidate. Certain medical conditions require alternative approaches.
Why does Mirelle require testing before prescribing BHRT?
Because hormones are powerful signaling molecules.
Before prescribing BHRT, Mirelle performs comprehensive metabolic and hormonal testing, which may include:
Serum and/or salivary hormone panels
Thyroid and adrenal evaluation
Inflammatory and cardiovascular risk markers
Metabolic and insulin markers
Genetic and ECM/fibrosis risk (when indicated)
Hormones are never prescribed without understanding the full internal terrain.
Is estrogen always part of BHRT for women?
No.
Estrogen is not universally appropriate and is contraindicated in certain patients, including those with:
Personal or genetic clotting risk
Estrogen-sensitive cancers
Certain cardiovascular or neurological risks
At Mirelle, estrogen is prescribed only when safe and necessary — and never in isolation without considering progesterone, testosterone, and neurosteroids.
Why isn’t estrogen alone enough?
Estrogen is only one part of a complex hormonal cascade.
Optimal hormone balance may also require:
Progesterone for neuroprotection and sleep
Testosterone for cognition, muscle, and libido (in women and men)
Pregnenolone and DHEA for adrenal and brain support
Treating estrogen alone often leads to incomplete relief or new symptoms.
What delivery methods are used for BHRT?
Depending on the patient and hormone, BHRT may be delivered via:
Transdermal creams or gels
Oral micronized formulations
Vaginal preparations (localized therapy)
Injectable therapies (when indicated)
The route is chosen to optimize absorption, safety, and physiologic signaling.
Is BHRT safe?
When properly prescribed and monitored, BHRT can be safe and highly effective.
Safety at Mirelle includes:
Thorough risk stratification
Conservative dosing
Ongoing monitoring
Clear contraindication screening
Regular follow-up and lab reassessment
Hormones are adjusted gradually — never aggressively.
How long does it take to feel results?
Some patients notice improvements within weeks, while others require several months for full neuroendocrine recalibration.
Hormone therapy is a process, not a quick fix.
Does BHRT help with brain health and mood?
Yes — hormones are neuroactive molecules.
Estrogen, progesterone, testosterone, and pregnenolone all influence:
Neurotransmitter balance
Cognitive clarity
Stress response
Mood stability
Sleep architecture
This is why Mirelle views menopause and andropause as neuroendocrine events, not just reproductive transitions.
Can BHRT be combined with other longevity therapies?
Yes — and this is where Mirelle excels.
BHRT is often integrated with:
Metabolic optimization programs
GLP-1 / GIP therapies (injectable only)
Peptide therapy
Body composition and muscle preservation strategies
Advanced skin and regenerative treatments
Everything is coordinated — nothing is siloed.
Why choose Mirelle for BHRT?
Because Mirelle does not follow trends — we follow physiology.
Patients choose Mirelle because we offer:
Advanced diagnostics
Medical-grade personalization
Conservative, science-based prescribing
A luxury, high-touch experience
Long-term partnership, not one-time prescriptions
Our Philosophy
Hormones do not act in isolation.
They communicate with the brain, metabolism, immune system, and tissues.
At Mirelle, we listen to the entire conversation.
Testosterone Replacement Therapy (TRT)
Precision Hormone Optimization for Men
What is Testosterone Replacement Therapy (TRT)?
Testosterone Replacement Therapy is a medically supervised treatment designed to restore testosterone levels to an optimal physiologic range when the body is no longer producing sufficient amounts on its own. Testosterone plays a critical role in energy, muscle mass, metabolic health, bone density, cognition, mood, and sexual function.
At Mirelle, TRT is not about maximizing levels — it is about restoring balance.
How do I know if I need TRT?
TRT is considered only after a comprehensive clinical evaluation, not symptoms alone. Candidates may experience:
Fatigue or loss of stamina
Decreased muscle mass or increased body fat
Brain fog, low motivation, or depressed mood
Reduced libido or erectile dysfunction
Poor recovery or sleep disruption
Diagnosis requires laboratory confirmation, including total and free testosterone, SHBG, and assessment of metabolic and cardiovascular risk.
How is TRT prescribed at Mirelle?
Mirelle follows a precision medicine approach, which includes:
Baseline hormone and metabolic testing
Cardiovascular and prostate risk screening
Evaluation of fertility goals
Conservative, individualized dosing
Ongoing monitoring and dose adjustments
TRT is never prescribed without understanding the entire endocrine and metabolic landscape.
Is TRT safe?
When properly prescribed and monitored, TRT can be safe and highly effective. Risks arise when therapy is given without appropriate screening, excessive dosing, or inadequate follow-up.
At Mirelle, safety includes:
Regular lab monitoring
Hematocrit and cardiovascular oversight
Prostate health evaluation when indicated
Adjustments based on symptoms and biomarkers
Can TRT be combined with other longevity treatments?
Yes. TRT is often integrated into a broader longevity and metabolic optimization program, which may include:
Body composition and muscle preservation strategies
GLP-1 / GIP therapy when appropriate
Peptide therapy
Nutritional and lifestyle optimization
Sexual health and performance programs
Everything is coordinated to support long-term health, not short-term gains.
Our Philosophy
Testosterone is not a performance drug.
It is a foundational hormone that must be respected, monitored, and optimized with intention.
✨ Exosomes & Biosomes
Ultra-advanced regenerative treatments that repair tissue, reduce inflammation, enhance skin radiance, support hair growth,
and accelerate healing.
Collagen & Fat Biostimulators (Sculptra®, Renuva®)
Regenerative Volume. Structural Rejuvenation. Long-Term Results.
Why chose Mirelle?
Because regeneration requires more than an injection.
Mirelle offers:
Deep understanding of tissue biology and aging
Expertise in metabolic and hormonal influences on collagen and fat
Advanced regenerative protocols
A luxury, high-touch experience grounded in medical science
Our Philosophy
True rejuvenation is not added — it is regenerated.
At Mirelle Institute for Anti-Aging Medicine, facial and body rejuvenation is not about instant filling — it is about restoring the biological scaffolding of youth through advanced collagen and fat-regenerative therapies.
What are collagen and fat stimulators?
Collagen and fat stimulators are biostimulatory treatments that encourage your body to rebuild its own tissue over time, rather than simply adding temporary volume.
They work by activating:
Fibroblasts (collagen-producing cells)
Extracellular matrix regeneration
Structural support beneath the skin
The result is gradual, natural-appearing rejuvenation that improves skin quality, firmness, and contour.
What is Sculptra® and how does it work?
Sculptra® is an FDA-approved injectable biostimulator made of poly-L-lactic acid (PLLA).
Once injected, Sculptra:
Stimulates fibroblasts to produce new collagen
Restores volume lost from aging, weight loss, or metabolic changes
Improves skin thickness and elasticity over time
Results develop gradually over several weeks to months and can last up to two years or longer.
What is Renuva® and how does it work?
Renuva:
Does not contain live fat cells
Encourages the body to repopulate the area with your own adipose tissue
Produces soft, natural, long-lasting volume
Renuva is ideal for areas of fat loss, contour irregularities, or hollowing.
How are Sculptra® and Renuva® different from dermal fillers?
Traditional fillers provide immediate volume by physically filling space.
Sculptra® and Renuva®:
Work gradually
Stimulate tissue regeneration
Improve skin quality and structure
Offer longer-lasting, more natural results
They are best suited for patients seeking biologic rejuvenation rather than instant correction.
Who is a good candidate for collagen or fat stimulators?
Candidates may include individuals experiencing:
Facial or body volume loss
Skin thinning or laxity
Post-weight-loss deflation (including after GLP-1 therapy)
Aging-related structural changes
At Mirelle, candidacy is determined through a comprehensive facial and body assessment, not a one-size-fits-all approach.
How long do results last?
Sculptra® results can last 24 months or longer with proper treatment planning.
Renuva® results may be long-lasting or permanent once fat regeneration occurs.
Longevity depends on:
Metabolic health
Lifestyle factors
Treatment area
Individual tissue response
Are these treatments safe?
When performed by trained medical professionals, both Sculptra® and Renuva® are considered safe.
At Mirelle, safety includes:
Proper patient selection
Advanced injection techniques
Thoughtful treatment spacing
Post-treatment monitoring
Can these treatments be combined with other therapies?
Yes. Collagen and fat stimulators are often combined with:
Energy-based skin tightening (Exilis Ultra®, RF microneedling)
Laser skin rejuvenation (LaseMD®)
Peptide and hormone optimization
Body composition and metabolic programs
This integrative approach enhances outcomes and longevity.
Regenerative PRFM & Vampire® Procedures
Non-surgical treatments that use your own growth factors to improve volume, texture, color, firmness, and sexual wellness.
Regenerative PRFM and Vampire® procedures are advanced, non-surgical treatments that harness your body’s own growth factors to stimulate natural healing and rejuvenation. Using high-concentration platelet-rich fibrin matrix (PRFM), these therapies activate collagen and elastin production, improve skin texture and tone, restore healthy color and firmness, and enhance volume in a subtle, natural way. Beyond aesthetic rejuvenation, select Vampire® procedures are also designed to support intimate and sexual wellness by improving tissue quality, circulation, and sensitivity. At Mirelle, these treatments are performed with medical precision to deliver biologic regeneration—not artificial enhancement—resulting in refreshed, resilient, and naturally revitalized results.
Vampire Face Lift®
Regenerative Facial Rejuvenation Using PRFM
The Vampire Face Lift® is a clinician-performed regenerative facial treatment designed to restore volume, improve skin quality, and stimulate natural collagen production—without surgery.
Using platelet-rich fibrin matrix (PRFM) derived from your own blood, this treatment delivers a concentrated source of growth factors that support tissue regeneration, improved circulation, and long-term skin vitality. When combined with structural fillers where appropriate, the Vampire Face Lift® enhances facial contours while maintaining a natural, elegant appearance.
Benefits may include:
Improved skin texture, tone, and elasticity
Restoration of youthful facial volume
Enhanced collagen and elastin production
Natural, progressive rejuvenation
This treatment is ideal for individuals seeking regenerative anti-aging solutions that work with the body’s biology rather than masking aging.
Vampire Breast Lift®
Non-Surgical Breast Rejuvenation with PRFM
The Vampire Breast Lift® is a non-surgical regenerative procedure designed to improve the appearance and quality of breast skin using PRFM technology.
PRFM is strategically injected to support collagen production, improve skin tone and texture, and enhance overall breast aesthetics. While not a substitute for surgical breast augmentation or lift, this treatment focuses on skin quality, firmness, and rejuvenation.
Benefits may include:
Improved skin elasticity and tone
Enhanced cleavage appearance
Reduction in stretch marks and skin laxity
Natural, non-surgical rejuvenation
This procedure is well suited for individuals seeking subtle, regenerative enhancement without implants or downtime.
Vampire Facial®
PRFM Skin Rejuvenation for Texture, Tone, and Glow
The Vampire Facial® combines microneedling with PRFM to stimulate collagen production and accelerate skin repair. This treatment enhances skin quality at the cellular level, improving texture, tone, and radiance.
By delivering growth factors directly into the skin, the Vampire Facial® supports natural healing pathways and long-term rejuvenation.
Benefits may include:
Improved skin texture and smoothness
Reduction in fine lines and acne scarring
Enhanced luminosity and hydration
Stimulation of collagen and elastin
This treatment is ideal for patients seeking skin revitalization without injectables or surgery.
O-Shot®
Regenerative Therapy for Women’s Sexual Health
The O-Shot® is a regenerative treatment designed to support female sexual health, sensitivity, and tissue vitality using PRFM.
By enhancing blood flow and tissue responsiveness, the O-Shot® supports the underlying physiology involved in arousal and sensation. This treatment is physician-performed and individualized based on anatomy and goals.
Benefits may include:
Improved sexual responsiveness and sensitivity
Enhanced vaginal tissue health
Support for urinary and pelvic wellness
Non-surgical, regenerative approach
The O-Shot® is often integrated into a broader functional and hormonal health strategy for optimal outcomes.
P-Shot®
P-Shot®
Regenerative Therapy for Men’s Sexual Health
The P-Shot® (Priapus Shot®) is a regenerative treatment designed to support male sexual health by enhancing blood flow, tissue regeneration, and cellular signaling using platelet-rich fibrin matrix (PRFM).
PRFM contains concentrated growth factors derived from your own blood that support vascular integrity and tissue responsiveness—key components of erectile function and sexual performance. At Mirelle Institute for Anti-Aging Medicine, this treatment is personally evaluated and performed by Dr. Corina Ianculovici, DNP, and is individualized based on anatomy, health history, and goals.
The P-Shot® is most effective when approached as part of a comprehensive evaluation of vascular, metabolic, hormonal, and nitric-oxide–dependent physiology, rather than as a stand-alone procedure.
Benefits may include:
Improved penile blood flow and tissue responsiveness
Support for erectile function and rigidity
Enhanced tissue quality and sexual confidence
A non-surgical, regenerative approach to male sexual wellness
Pre-Procedure Preparation
To support optimal outcomes, we recommend that patients obtain and become familiar with a medical-grade penile pump prior to scheduling the P-Shot®.
Controlled penile pumping supports tissue expansion, vascular responsiveness, and post-procedure integration of regenerative signals when used appropriately. This preparation may enhance comfort and support the body’s response to treatment.
For quality, safety, and clinical reliability, we recommend the penile pump designed by Dr. Joel Kaplan, which meets medical standards and is commonly incorporated into regenerative urology and sexual wellness protocols.
Detailed guidance on appropriate use and timing will be provided as part of your personalized care plan.
A Thoughtful, Integrated Approach
Regenerative therapies such as the P-Shot® are influenced by overall health. For this reason, many patients benefit from a functional medicine consultation to assess factors such as:
- Cardiovascular and endothelial health
- Nitric oxide signaling and circulation
- Metabolic health and insulin sensitivity
- Hormonal balance
Addressing these elements helps ensure that regenerative treatments are aligned with internal physiology for the most meaningful and sustainable outcomes.
PRFM Joint Injections
Regenerative Support for Joint Health and Mobility
PRFM joint injections provide a regenerative approach to joint discomfort, stiffness, and reduced mobility. By delivering concentrated growth factors directly into affected joints, PRFM supports tissue repair and inflammation modulation.
Benefits may include:
Improved joint comfort and mobility
Support for tissue healing
Reduced reliance on medications
Non-surgical alternative for joint support
PRFM joint therapy is commonly used for knees, shoulders, hips, and other joints affected by wear, injury, or inflammation.
PRFM for Hair Loss
Regenerative Hair Restoration for Men and Women
PRFM for hair loss is a regenerative treatment designed to support hair follicle health, scalp circulation, and hair density.
PRFM delivers growth factors that help stimulate dormant follicles and improve the scalp environment necessary for healthy hair growth.
Benefits may include:
Improved hair thickness and density
Reduced hair shedding
Enhanced scalp health and circulation
Natural, non-surgical hair restoration
This treatment is effective for both men and women and is often combined with hormonal and metabolic optimization for best results.
Facial Balancing & Aesthetic Rejuvenation
At Mirelle, beauty is approached as an art form guided by medical precision. All injectable treatments are personally performed by Dr. Ianculovici, DNP, FAAMFM, AMAAM-HP, AGNP, who uses a refined combination of dermal fillers, neuromodulators, and regenerative techniques to sculpt, harmonize, and lift the face while preserving each patient’s natural features. Every treatment is thoughtfully customized to restore balance, soften signs of aging, and support long-term tissue health—delivering results that are elegant, natural, and never “done.”
At Mirelle, all injectable treatments are performed exclusively by Dr. Corina Ianculovici, DNP, FAAMFM. This ensures a deep understanding of facial anatomy, vascular safety, aging physiology, and regenerative biology. This level of expertise allows for precise, conservative treatments that enhance natural beauty while minimizing risk—an essential standard when sculpting the face with advanced injectables.
Signature Statement from Dr. Ianculovici, DNP, FAAMFM, ABAAM-HP, AGNP
“True aesthetic medicine is not about changing how someone looks—it is about restoring harmony, structure, and confidence in a way that feels authentic to the individual and respectful to their anatomy. My goal is for my patients to look refreshed, radiant, and completely themselves.”
— Dr. Corina Ianculovici
Our Before & After Philosophy
At Mirelle, before-and-after results are never about dramatic transformation. They reflect subtle refinement, improved structure, and restored balance. Each treatment plan is guided by facial proportions, tissue quality, and long-term aging patterns—not trends. The result is aesthetic rejuvenation that appears effortless, elegant, and timeless.
Skin Tightening & Resurfacing
Genius® RF Microneedling & LaseMD® enhance skin elasticity, tone, and radiance for a youthful, luminous complexion.
Genius® RF Microneedling and LaseMD® work synergistically to restore skin firmness, refine texture, and revive radiance at the cellular level. Genius® delivers precise radiofrequency energy through microneedles to stimulate collagen remodeling and improve skin elasticity from within, while LaseMD® creates controlled microchannels that accelerate cellular renewal, enhance tone, and optimize the absorption of regenerative serums. Together, these advanced technologies promote smoother, tighter, and more luminous skin—revealing a youthful complexion that looks refreshed, refined, and naturally vibrant.
Luxury Medical-Grade Skincare
Proprietary Luxury Medical-Grade Skincare- Dr. Ianculovici Rx™
Dr. Ianculovici Rx™ is a curated line of luxury, medical-grade skincare formulated to work in harmony with your in-clinic treatments. These clinical formulations are designed to restore optimal moisture balance, strengthen the dermal barrier, and enhance cellular renewal—extending and amplifying the results of advanced aesthetic procedures. By supporting collagen integrity, improving skin resilience, and refining luminosity at the cellular level, Dr. Ianculovici Rx™ helps maintain a radiant, healthy complexion long after you leave the treatment room.
AnteAGE® MD Regenerative Skincare
AnteAGE® MD is an advanced, physician-dispensed regenerative skincare system powered by bone-marrow–derived growth factors and cytokines. Designed to support cellular communication and dermal repair, AnteAGE® MD enhances collagen production, improves skin texture, and accelerates recovery following aesthetic procedures. At Mirelle, AnteAGE® MD is strategically integrated into treatment plans to calm inflammation, restore skin vitality, and promote a smoother, firmer, more luminous complexion—making it an ideal complement to microneedling, laser, and regenerative therapies.
Prescription GHK-Cu Peptide Skincare
GHK-Cu (Copper Tripeptide-1) is a prescription regenerative peptide skincare formulations to support advanced skin repair and rejuvenation. Clinically studied for its role in collagen and elastin synthesis, extracellular matrix remodeling, and skin barrier restoration, GHK-Cu helps improve firmness, texture, and overall skin resilience. At Mirelle, prescription GHK-Cu skincare is used strategically to accelerate healing after procedures, reduce inflammation, and strengthen dermal integrity—resulting in smoother, healthier, and visibly revitalized skin with continued use.
Prescription Estriol Face Cream
Prescription estriol face cream is a bio-identical, clinician-guided therapy designed to address hormonally driven skin aging. Estriol supports collagen density, improves skin thickness, enhances hydration, and restores elasticity by activating estrogen receptors in the skin—without the systemic exposure associated with stronger estrogens. At Mirelle, estriol face cream is carefully prescribed to appropriate candidates to improve firmness, smooth fine lines, and revive radiance, making it especially beneficial for peri- and post-menopausal skin experiencing thinning, dryness, and loss of vitality.
Longevity Isn’t a Trend — It’s a Lifestyle
We work with clients who understand that aging well is intentional, strategic, and deeply personal.
Whether your goal is to:
- rejuvenate your skin
- enhance your confidence
- boost your metabolism
- optimize hormones
- increase vitality
- refine your appearance
- prevent long-term decline
— our treatments are designed to support you at every level.
A Luxury Experience Tailored to You
Your visit includes:
- extended appointments
- personalized diagnostics
- discreet, serene environment
- concierge-level communication
- ongoing monitoring
- access to elite memberships via our app
You receive the time, attention, expertise, and artistic precision that define the Mirelle standard.
Start Your Longevity Transformation
Experience a new era of anti-aging medicine — where science, personalization, and luxury meet.
Your journey to timeless vitality begins here.
