Total Skin Solutions™
A Comprehensive Approach to Skin Quality, Structure, and Longevity
Total Skin Solutions™ at the Mirelle Institute combines Genius® RF microneedling and LaseMD® laser technology to support collagen production, skin texture, tone, and long-term skin quality through a layered, longevity-focused approach.
Discover Total Skin Solutions™& The Power of Stem Cell
The AnteAge MD™Exosomes & Cytokines
Healthy, radiant skin reflects more than surface appearance—it is influenced by collagen integrity, cellular turnover,
vascular support, and the skin’s ability to repair and renew over time.
Total Skin Solutions™ at the Mirelle Institute for Anti-Aging Medicine is a thoughtfully designed, combination treatment
that integrates Genius® RF Microneedling and LaseMD® Thulium Laser technology to address skin texture, tone, firmness, and overall skin quality within a single, cohesive protocol.
This approach is not designed for temporary correction, but for progressive, biologically supported skin renewal.
Why a Combined Treatment Approach Matters
Skin aging is multifactorial. Collagen depletion, uneven pigment, loss of elasticity, and impaired cellular communication all contribute to visible changes in skin quality.
By combining radiofrequency microneedling with targeted laser energy, Total Skin Solutions™ addresses multiple layers of the skin—supporting structural remodeling, cellular signaling, and surface refinement simultaneously. This layered strategy allows results to develop in a balanced, natural manner over time.
Genius® RF Microneedling
Precision-Guided Collagen and Structural Support
Genius® RF Microneedling is an advanced treatment that delivers radiofrequency energy through insulated microneedles at precisely controlled depths. This technology is designed to stimulate collagen and elastin production while preserving the surrounding tissue.
The system’s intelligent feedback mechanisms allow for consistent energy delivery tailored to individual skin needs, supporting improvements in firmness, texture, and elasticity. Treatment planning is guided by skin quality, anatomy, and long-term goals rather than standardized settings.
LaseMD® Thulium Laser
Targeted Skin Renewal and Tone Refinement
LaseMD® is a non-ablative thulium laser designed to create microscopic channels in the skin, supporting controlled resurfacing and enhanced delivery of topical regenerative serums when appropriate.
This technology may help improve uneven tone, fine lines, sun damage, and textural irregularities while remaining suitable for a wide range of skin types and seasons. Its versatility allows it to be safely incorporated into comprehensive skin renewal protocols year-round.
What to Expect After Treatment
Following Genius® RF Microneedling, mild redness and swelling are common and typically resolve within 24–36 hours, though some individuals may experience residual effects for several days. LaseMD® treatment may result in temporary dryness or mild flaking as the skin renews.
During this recovery period, important biologic processes are taking place beneath the surface—including collagen remodeling, cellular signaling, and improved skin matrix organization. These processes continue over weeks to months, contributing to progressive improvement in skin quality.
Downtime is generally minimal, allowing most individuals to resume daily activities shortly after treatment with appropriate post-care guidance.
Skin Renewal Rooted in Longevity Science
Total Skin Solutions™ is aligned with a functional aesthetics and longevity framework, recognizing that durable skin health depends on both external treatment and internal support.
For some patients, this protocol may be integrated with regenerative therapies, medical-grade skincare, or internal wellness strategies to further support skin resilience, repair capacity, and long-term results.
Who May Benefit From Total Skin Solutions™
This treatment may be appropriate for individuals seeking to:
- Improve skin texture and tone
- Support collagen and skin firmness
- Address fine lines, sun damage, or uneven pigmentation
- Enhance overall skin quality without aggressive resurfacing
- Pursue a biologically informed, long-term approach to skin health
A consultation allows for assessment of skin needs and development of a personalized treatment plan.
A Refined Path to Skin Health and Radiance
At Mirelle, skin treatments are never isolated procedures. They are part of an integrated approach designed to support how skin functions, repairs, and ages over time.
Total Skin Solutions™ reflects this philosophy—bringing together advanced technology, clinical precision, and longevity-focused care to support skin that appears balanced, resilient, and naturally radiant.
Begin Your Personalized Skin Consultation
Your skin deserves a plan grounded in expertise, biology, and intention. A consultation allows us to determine whether Total Skin Solutions™ aligns with your skin goals and long-term vision for skin health.
Inflammation and Repair Response
1. Micro-Injuries: The microneedles of the Genius RF device create controlled micro-injuries in the skin's surface. These tiny punctures are intentional and trigger the body's natural healing response.
2. Inflammatory Phase: The initial pinkness and swelling are indicative of the inflammatory phase of the healing process. Blood vessels in the treated area dilate to allow immune cells and growth factors to reach the site of injury.
Collagen Stimulation
3. Fibroblast Activation: Fibroblasts, the cells responsible for collagen synthesis, become activated. These cells play a crucial role in cell repair and regeneration.
4. Collagen Production: The body responds to the micro-injuries by producing new collagen fibers. Collagen is a key cellular protein that provides strength and elasticity to the skin.
5. Neocollagenesis: The term "neocollagenesis" refers to the formation of new collagen. During the downtime, this process is underway, and the new collagen gradually replaces the damaged or aged collagen in the treated area.
Tissue Remodeling
6. Remodeling Phase: As the inflammatory response subsides, the remodeling phase begins. This phase involves the reorganization of collagen and other cellular components, resulting in improved skin texture and firmness.
Post-Treatment Care
7. Resolution of Pinkness and Swelling: The pinkness and swelling observed during downtime are natural responses to the skin's healing process. Adequate post-treatment care, including gentle cleansing, moisturizing, and sun protection, can support the recovery process and help minimize these effects.
Patient Experience
8. Gradual Improvement: While the initial downtime is temporary, the collagen stimulation and remodeling continue over the following weeks and months. Patients typically notice gradual improvements in skin texture, tone, and tightness.
In summary, the downtime after Genius® RF Microneedling is a crucial part of the treatment process. It signifies the activation of the body's natural repair mechanisms, leading to the stimulation of collagen production and ultimately contributing to the rejuvenation of the skin. The controlled nature of the micro-injuries and the subsequent healing response result in long-term improvements in skin quality and appearance.
How Does Genius® Compare With Other RF Microneedling Treatments?
Genius® RF Microneedling by Lutronic stands out significantly when compared to other RF microneedling devices on the market. Here's why:
Superior Results with Minimal Downtime
Genius® not only delivers superior results but does so with minimal downtime. This means you can achieve remarkable improvements in skin texture and appearance without a prolonged recovery period.
Safety First
Genius® is recognized as the safest RF microneedling device of its kind. The advanced technology and design prioritize safety, ensuring a secure and effective treatment experience.
Higher Needle Count for Enhanced Energy Delivery
With 49 needles per tip (compared to 24 needles with Morpheus 8), Genius® allows for the safe delivery of more energy. This increased energy emission contributes to better results, particularly in terms of skin tightening.
Finer Needles for Denser Epidermal Injury
The Genius® needles are finer, causing smaller yet denser epidermal injury. This design minimizes the risk of bruising, bleeding, or scratches often associated with other microneedling treatments.
In summary, Genius® RF Microneedling not only sets itself apart by delivering remarkable results but also ensures a safer and more comfortable experience. The higher needle count, safety features, and finer needle design make it an exceptional choice for individuals seeking effective and advanced microneedling treatments.
LaseMD® Thulium Laser: Elevating Laser Resurfacing to New Heights
1. Thulium Technology Precision: Harnesses thulium technology for precise, targeted energy delivery.
2. Versatility Across Skin Types: Safe and effective for various skin types, ensuring inclusivity.
3. Fractional Technology Comfort: Utilizes fractional laser technology for minimal discomfort during the procedure.
4. Swift Recovery, Enhanced Results: Offers remarkable results with significantly shortened downtime.
5. Comprehensive Skin Concerns: Addresses fine lines, wrinkles, pigmentation, and skin texture in one session.
6. Year-Round Treatment:
Safe for treatment throughout the year, providing flexibility.
7. Customizable for Individual Needs:
Tailorable settings for personalized treatment plans.
Experience the next level of laser resurfacing – LaseMD® combines precision, versatility, and rapid recovery for unparalleled skin rejuvenation.
Laser Skin Rejuvenation
LASEMD®ULTRA
Why LaseMD® Ultra
LaseMD® Ultra is a non-ablative fractional thulium laser designed to support skin renewal, tone refinement, and overall skin quality across a wide range of skin types. Operating at a 1,927 nm wavelength, this technology creates controlled micro-channels in the skin, encouraging cellular turnover and collagen support without the extended downtime associated with traditional resurfacing lasers.
Unlike more aggressive laser modalities, LaseMD® Ultra allows for a highly customizable treatment approach. Settings can be adjusted to align with individual skin concerns, treatment goals, and seasonal considerations—making it suitable for year-round use within a comprehensive skin health strategy.
This versatility enables gradual, progressive improvement in skin texture, pigmentation irregularities, and photodamage while maintaining patient comfort and minimal interruption to daily activities.
Clinical Advantages of LaseMD® Ultra
- Adjustable energy delivery allows treatment of multiple facial and body areas with precision
- May support improvement in pigment-related concerns, including melasma, when appropriately selected
- Designed for a broad range of skin tones and types
- Non-ablative approach supports skin renewal with minimal downtime
- Can contribute to visible refinement in tone, texture, and overall skin clarity as part of a layered treatment plan
How Does LaseMD® Ultra Work?
How Does LaseMD® Ultra Work?
LaseMD® Ultra is a non-ablative fractional laser treatment designed to support skin renewal by delivering controlled thermal energy into the skin without removing the outer layer. The laser creates microscopic treatment zones that stimulate collagen remodeling and cellular turnover while preserving the skin’s surface integrity.
Because the treatment is non-ablative, it supports visible skin refinement without the extended recovery typically associated with traditional resurfacing lasers. This makes LaseMD® Ultra well suited for individuals seeking progressive improvement in skin tone, texture, and clarity with minimal disruption to daily life.
LaseMD® Ultra is highly customizable and can be adjusted to align with individual skin type, concerns, and treatment goals. Depending on the settings used, treatments may range from gentle skin renewal to more intensive resurfacing within a controlled, non-ablative framework.
During treatment, patient comfort is supported through the use of topical anesthetic and cooling measures. Most individuals describe the sensation as mild warmth as the laser passes over the skin. Post-treatment effects are typically limited and temporary, allowing for a smooth return to regular activities with appropriate aftercare.
Is LaseMD® Ultra painful?
LaseMD® Ultra is generally well tolerated. Most patients describe a mild warming sensation during treatment. Comfort measures such as topical anesthetic and cooling are used to support a comfortable experience.
What is the downtime after LaseMD® Ultra?
Downtime is typically minimal. Some individuals experience mild redness, dryness, or flaking for a few days following treatment. Most patients are able to return to normal activities shortly after with appropriate post-care guidance.
When will I see results from LaseMD® Ultra?
Some improvement in skin tone and texture may be noticed as the skin heals, while collagen remodeling and deeper skin renewal continue to develop gradually over several weeks.
Is LaseMD® Ultra safe for all skin types?
LaseMD® Ultra is designed to be suitable for a wide range of skin types and tones when customized appropriately. Treatment settings are selected based on individual skin characteristics and goals.

BEFORE /AFTER 3 LASE MD ULTRA TREATMENTS
BEFORE / AFTER 2 LASE MD ULTRA TREATMENTS
The Synergy of Genius® RF and LaseMD®: Elevating Skin Rejuvenation to New Heights
When combined, the Genius™ RF Microneedling and LaseMD Thulium Laser create a powerful synergy. The microneedling procedure primes the skin, allowing the LaseMD™ laser to penetrate more effectively. This dynamic duo addresses a wide range of skin concerns, including:
Fine Lines and Wrinkles
Softening the appearance of lines for smoother skin.
Uneven Skin Tone
Correcting pigmentation issues to reveal a more balanced complexion.
Texture Irregularities
Improving skin texture and minimizing the appearance of imperfections.
Collagen Remodeling
Stimulating collagen production for firmer, more resilient skin.
Total Skin Solutions™ + AnteAGE MD™ Serum Enhancement: A Layered Approach to Skin Renewal and Longevity
Total Skin Solutions™ may be further enhanced with the optional addition of AnteAGE MD™ cytokine and growth factor–based serums, applied during in-office treatment to support skin recovery and quality.
This integrated approach pairs the precision of Genius® RF microneedling and LaseMD® laser technology with advanced biologic formulations designed to support cellular signaling and the skin’s natural repair processes. When used together, these modalities allow for a more comprehensive strategy—addressing structural support, surface refinement, and skin resilience within a single, thoughtfully designed protocol.
The AnteAGE MD™ serum enhancement is intended to complement the treatment process by supporting collagen remodeling, skin barrier function, and overall skin vitality as the skin renews over time. This option is selected based on individual skin needs and treatment goals and is incorporated within a longevity-focused care framework.
Refinement Rooted in Science and Intention
At Mirelle, advanced skin treatments are approached as part of a broader vision for skin health—not as isolated procedures. The combination of Total Skin Solutions™ with targeted serum support reflects a commitment to layered, biologically informed care that prioritizes durability, balance, and natural-looking results.
This option may be appropriate for individuals seeking to elevate their skin renewal experience through a more comprehensive, supportive approach.
Discover how Total Skin Solutions™, with or without advanced serum support, can be tailored to your skin within a refined, longevity-focused model of care.

The AnteAGE MD™ serum enhancement may be incorporated into Total Skin Solutions™ to support cellular signaling, collagen remodeling, and overall skin quality within a layered, longevity-focused treatment protocol.
Begin Your Personalized Skin Consultation
A consultation allows for assessment of your skin, discussion of available enhancements, and development of a treatment plan aligned with your long-term skin health goals.
Exilis Ultra®: Non-Invasive Skin Tightening and Body Contouring
Exilis Ultra® is a non-invasive treatment that supports skin tightening for the face and body while also addressing localized fat reduction in select body areas through controlled radiofrequency energy and cooling within a longevity-focused approach.

Exilis Ultra® is uniquely versatile in its ability to address multiple concerns within a single technology platform.
For the body, it may be used to support both localized fat reduction and skin tightening—helping improve contour and firmness simultaneously in areas where laxity and adiposity coexist.
For the face, Exilis Ultra® is applied specifically for skin tightening and tissue support, addressing mild to moderate laxity without needles or downtime. This adaptability allows treatments to be customized based on anatomy, goals, and treatment area, making Exilis Ultra® a valuable option within a comprehensive body contouring and skin tightening strategy.
Exilis Ultra® is offered at the Mirelle Institute for Anti-Aging Medicine as a non-invasive approach to supporting skin firmness, contour, and tissue quality. This technology uses a controlled combination of radiofrequency energy and cooling to deliver thermal stimulation at multiple tissue depths while protecting the skin’s surface.
Unlike treatments that rely on needles or ablative injury, Exilis Ultra® is designed to support collagen remodeling and tissue tightening without puncturing the skin or requiring anesthesia. Energy delivery can be adjusted based on individual anatomy and treatment goals, allowing both superficial and deeper layers to be addressed within a single session.
This approach makes Exilis Ultra® well suited for individuals seeking gradual, natural-looking improvement in skin laxity with minimal disruption to daily life. Treatments are generally well tolerated and do not require downtime, making them easy to incorporate into a comprehensive aesthetic or longevity-focused care plan.
A Thoughtful Alternative Within a Functional Aesthetics Framework
At Mirelle, Exilis Ultra® is selected as part of a broader strategy for skin health and structural support. Rather than positioning one technology as superior to all others, treatment planning considers skin quality, degree of laxity, lifestyle factors, and long-term goals.
Exilis Ultra® may be used on its own or layered with other non-invasive or regenerative treatments to support durable results that evolve progressively over time—reflecting a commitment to balance, safety, and longevity.
What is Exilis Ultra®?
Exilis Ultra® is a non-invasive skin tightening treatment that uses controlled radiofrequency energy combined with cooling to support collagen remodeling and tissue firmness without needles or anesthesia.
How does Exilis Ultra® tighten the skin?
The treatment delivers targeted thermal energy to stimulate collagen and elastin activity at multiple tissue depths while protecting the skin surface through integrated cooling.
Can Exilis Ultra® be used for both fat reduction and skin tightening?
Yes. Exilis Ultra® may be used on the body to support localized fat reduction while simultaneously tightening the skin in treated areas. On the face, it is used specifically to support skin tightening and tissue firmness. Treatment settings and goals are customized based on the area being treated and individual needs.
How does Exilis Ultra® address localized fat?
Exilis Ultra® uses controlled radiofrequency energy to gently heat targeted tissue in select body areas. This thermal stimulation may disrupt fat cells and support the body’s natural metabolic processes for clearing treated fat over time, while simultaneously encouraging skin tightening through collagen remodeling. Treatment parameters are customized based on the area treated and individual goals.
Is Exilis Ultra® painful?
Exilis Ultra® is generally well tolerated. Most patients describe a warm sensation during treatment, with comfort supported by real-time cooling technology.
Is there downtime after Exilis Ultra®?
There is typically no downtime. Patients can return to normal activities immediately following treatment.
Which areas can be treated with Exilis Ultra®?
Exilis Ultra® may be used on the face and body to address skin laxity and contour concerns, depending on individual needs and treatment goals.
How many treatments are recommended?
A series of 4-8 treatments is often recommended for optimal results. The number and frequency are determined during consultation based on skin condition and desired outcomes.
When will I see results from Exilis Ultra®?
Some patients notice early improvements in skin firmness, while collagen remodeling continues to develop gradually over several weeks.
Who is a good candidate for Exilis Ultra®?
Individuals seeking non-invasive skin tightening with minimal disruption to daily life may be good candidates following a personalized assessment.
SkinPen® Microneedling
Why Do We Like the SkinPen® for Microneedling?
- SkinPen is the first FDA-cleared microneedling device
- SkinPen is proven to be safe and effective, delivering long lasting results
- A quick-and-easy treatment with little to no downtime
- SkinPen is proven to improve the appearance of acne scars and wrinkles on the face
Microneedling: Your Path to Radiant, Rejuvenated Skin
Microneedling is a transformative treatment that stimulates your skin's natural healing process, improving texture, tone, and elasticity. At Mirelle Institute for Anti-Aging Medicine, we elevate microneedling to the next level by combining it with advanced, scientifically proven enhancements tailored to your unique skin goals. Discover the five innovative microneedling options we offer:
1. Microneedling with Botox and Hyaluronic Acid (HA) Unveil Smooth, Hydrated, and Glowing Skin
This revolutionary approach combines the collagen-boosting benefits of microneedling with micro-doses of botox and deeply hydrating hyaluronic acid serum. Botox minimizes fine lines, tightens pores, and smooths the skin’s surface, while HA deeply nourishes and plumps your skin.
Benefits:
- Instantly glowing and hydrated skin.
- Reduced fine lines, wrinkles, and pore size.
- A non-invasive alternative to achieving a lifted, youthful look with minimal downtime.
This is the perfect option for those seeking quick yet noticeable improvements, making it ideal before special events or as part of a routine skincare regimen.
2. Microneedling with Exosomes Cutting-Edge Science Meets Skin Rejuvenation
Exosomes are the next frontier in skin health, harnessing the power of biologic communication to promote regeneration and repair at a deeper level. Combined with microneedling, exosomes deliver potent growth factors and peptides directly to the skin.
Benefits:
- Enhanced skin healing and accelerated recovery.
- Improved skin texture and reduced discoloration.
- Long-term rejuvenation, reducing fine lines and improving elasticity.
This option is perfect for anyone looking to leverage advanced regenerative science for dramatic, lasting results.
3. Microneedling with Stem Cell & Cytokines Regenerate, Restore, and Renew
Stem Cell and cytokines work synergistically to boost collagen and elastin production, making this microneedling option a powerful anti-aging treatment. These naturally derived components restore skin vitality from the inside out.
Benefits:
- Profound anti-aging effects, including reduced wrinkles and firmer skin.
- Enhanced repair of damaged or scarred cell.
- Improved skin tone and texture for a youthful appearance.
Ideal for individuals concerned with aging skin, scars, or dullness, this treatment is a game-changer for complete skin rejuvenation.
4. Microneedling with PRP (Platelet-Rich Plasma)
The Power of Your Own Growth Factors
Popularly known as the "Vampire Facial," this treatment uses your own plasma, packed with growth factors, to supercharge the microneedling process. PRP (Platelet-Rich Plasma) stimulates collagen production and accelerates the skin's natural healing process.
Benefits:
- Reduced fine lines, wrinkles, and acne scars.
- Faster healing with long-lasting rejuvenation.
- Naturally boosts skin's glow and radiance.
This option is perfect for individuals seeking a more natural approach to skin rejuvenation, using their body’s own healing power.
5. Microneedling with Collagen Ampule Nourish Your Skin with Collagen-Rich Infusion
Microneedling with a collagen ampule enhances the delivery of essential peptides and nutrients to your skin, promoting elasticity and hydration. This treatment is a favorite for those aiming to prevent early signs of aging or maintain youthful, radiant skin.
Benefits:
- Boosts collagen production for firmer, more supple skin.
- Deeply hydrates and nourishes for a luminous glow.
- Prevents and reduces early signs of aging.
This option is perfect for individuals who want to support their skin’s structure and hydration while addressing fine lines and dullness.

Why Choose Mirelle Institute for Your Microneedling Treatments?
At Mirelle Institute for Anti-Aging Medicine, we understand that no two skins are alike. Our personalized approach ensures that each treatment is tailored to your unique needs, helping you achieve radiant, healthy, and youthful skin. Whether you’re looking to target fine lines, acne scars, or overall skin rejuvenation, our expert providers are here to guide you on your journey to confidence and beauty.
Book Your Microneedling Treatment Today
Reclaim your glow and let your inner beauty shine through. Contact us today to schedule your consultation and discover the microneedling option that’s perfect for you!
Can’t find what you’re looking for? Simply call our friendly staff on 732-292-0100









