Under the clinical direction of Dr. Corina Ianculovici, DNP, FAAMFM, Mirelle Institute provides advanced Bio-Identical Hormone Replacement Therapy (BHRT) designed to restore physiological balance and systemic vitality. Unlike synthetic alternatives, our precision-dosed protocols utilize hormones that are molecularly identical to those your body produces naturally, helping patients in Wall Township and Manasquan reverse the debilitating symptoms of perimenopause, menopause, and andropause.

Understanding the Impact of Hormonal Decline

Aging is often characterized by a cascade of undesirable biological shifts. For both men and women, hormonal decline can lead to systemic issues including:

• Metabolic & Physical: Loss of lean muscle mass, increased insulin resistance, and diminished bone density.
• Cognitive & Emotional: Memory impairment, "brain fog," and increased systemic inflammation.
• Vitality & Wellness: Chronic joint pain, sexual dysfunction, and cardiovascular health concerns.

While these changes affect men, women often experience a more abrupt decline during perimenopause and menopause, which can be life-altering. Clinical observations and social statistics even suggest a correlation between the onset of menopause and increased rates of marital strain, often due to the significant physiological and emotional toll of untreated symptoms.

The Truth About the Women’s Health Initiative (WHI) Study

Much of the "hormone stigma" stems from the 2002 Women’s Health Initiative study. While headlines reported frightening increases in breast cancer and stroke risk, it is critical to look at the absolute risk and the type of hormones used:

• Statistical vs. Absolute Risk: While percentage increases sounded high, only 2.5% of women in the study actually experienced these health events.
• Synthetic vs. Bio-Identical: The study used equine-derived estrogens (Premarin) and synthetic progestins, which differ significantly from human biology.

Why Bio-Identical Hormones are the Superior Choice

Synthetic hormones often give "incomplete messages" to your cells, leading to side effects that cause roughly 50% of patients to discontinue treatment within a year.

Bio-Identical Estradiol (E2) and Progesterone offer a natural alternative:

• Molecular Match: They possess the exact chemical structure your body was born with, allowing for seamless cellular communication.
• Vascular Protection: Unlike equine estrogens, natural estradiol supports the production of Nitric Oxide, an essential molecule for vascular health and longevity.
• Systemic Benefits: Proper estrogen levels support over 400 functions, including collagen maintenance for skin, neurotransmitter support (serotonin/dopamine), and heart health.

The Mirelle Institute Approach to Hormone Health

We believe that hormone replacement is not a "one-size-fits-all" solution. Our protocols emphasize:

• Clinical Monitoring: Your health status and hormone levels are closely monitored to ensure safety and efficacy.
• Transdermal Precision: We utilize high-quality compounded transdermal creams to ensure optimal absorption and bypass first-pass liver metabolism.
• Holistic Balancing: Small, precise adjustments can drastically improve your mental and physical health, helping you regain the quality of life you deserve.

Schedule Your Consultation with Dr. Ianculovici, DNP, FAAMFM, ABAAM, AGNP